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Neurology
Emily Hughes and Eshita Kapoor, chapter editors Helen Genis and Alex Sapa, associate editors
Melissa Allwood and Joshua Mehta, EBM editors
Dr. Esther Bui and Dr. Xavier Montalban, staff editors
Acronyms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Approach to the Neurological Complaint . . . . . . 2
Lesion Localization
The Neurological Exam . . . . . . . . . . . . . . . . . . . . . 3
General Exam and Mental Status Cranial Nerve Exam
Motor Exam
Sensory Exam
Coordination Exam and Gait
Basic Anatomy Review . . . . . . . . . . . . . . . . . . . . . 6
Lumbar Puncture . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Approach to Common Presentations . . . . . . . . . . 9
Weakness Numbness/Altered Sensation Gait Disturbance
Cranial Nerve Deficits . . . . . . . . . . . . . . . . . . . . . 11
Movement Disorders . . . . . . . . . . . . . . . . . . . . . . 29
Function of the Basal Ganglia Overview of Movement Disorders Movement Disorders
Parkinson’s Disease
Other Parkinsonian Disorders Huntington’s Disease Dystonia
Tic Disorders
Tourette’s Syndrome
Cerebellar Disorders . . . . . . . . . . . . . . . . . . . . . . 34
Wernicke-Korsakoff Syndrome Cerebellar Ataxias
Vertigo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .OT12
Motor Neuron Disease . . . . . . . . . . . . . . . . . . . . 35
Amyotrophic Lateral Sclerosis Other Motor Neuron Diseases
Peripheral Neuropathies . . . . . . . . . . . . . . . . . . . 36 Neuromuscular Junction Diseases . . . . . . . . . . . 38
Myasthenia Gravis
Lambert-Eaton Myasthenic Syndrome Botulism
Myopathies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
Clinical Approach to Muscle Diseases Myotonic Dystrophy
Pain Syndromes . . . . . . . . . . . . . . . . . . . . . . . . . . 41
Approach to Pain Syndromes Neuropathic Pain
Trigeminal Neuralgia
Postherpetic Neuralgia
Painful Diabetic Neuropathy Complex Regional Pain Syndromes
Headache . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44
Migraine Headaches
Sleep Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . 46
Overview of Sleep
Disturbances of Alertness and Sleep
CNS Infections . . . . . . . . . . . . . . . . . . . . . . . . . ID18
Spinal Cord Syndromes . . . . . . . . . . . . . . . . .NS29
Stroke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .48
Terminology
Pathophysiology
Assessment and Treatment of Ischemic Stroke Primary and Secondary Prevention of Ischemic Stroke
Cerebral Hemorrhage
Neurocutaneous Syndromes . . . . . . . . . . . . . . P77
Multiple Sclerosis . . . . . . . . . . . . . . . . . . . . . . . . 52 Common Medications . . . . . . . . . . . . . . . . . . . . 54 Landmark Neurology Trials . . . . . . . . . . . . . . . . . 55 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
CN I CN II CN III
CN IV CN V CN VI
CN VII CN VIII CN IX
CN X CN XI CN XII
Neuro-Ophthalmology . . . . . . . . . . . . . . . . . . . . 14
Optic Neuritis
Anterior Ischemic Optic Neuropathy (AION) Amaurosis Fugax
Optic Disc Edema
Optic Disc Atrophy
Abnormalities of Visual Field . . . . . . . . . . . . . .
. 15 . 15
. 17 . 18
. 20
. 28 . 29
Abnormalities of Eye Movements
Disorders of Gaze Internuclear Ophthalmoplegia Diplopia
Nystagmus
Abnormalities of Pupils
. . . . . . . . . .
Nutritional Deficiencies and Toxic Injuries . . . Seizure Disorders and Epilepsy . . . . . . . . . . . .
Seizure
Status Epilepticus
Behavioural Neurology . . . . . . . . . . . . . . . . . . .
Acute Confusional State/Delirium
Mild Neurocognitive Disorder
Major Neurocognitive Disorder
Major or Mild NCD due to Alzheimer’s Disease Major or Mild NCD with Lewy Bodies
Major or Mild Frontotemporal NCD Major or Mild Vascular NCD Creutzfeldt-Jakob Disease
Aphasia
Apraxia Agnosia
Mild Traumatic Brain Injury
. . . . . . . . . . . . . . .
Neuro-Oncology . . . . . . . . . . . . . . . . . . . . . . . .
Paraneoplastic Syndromes Tumours of the Nervous System
Toronto Notes 2019
Neurology N1
