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 Toronto Notes 2019
Common Medications
Emergency Medicine ER61
Table 41. Commonly Used Medications (continued)
 Drug
Morphine Naloxone
Nitroglycerin
Percocet 10/325® Phenytoin
Polysporin® Propofol
Salbutamol Thiamine Tylenol #3®
Dosing Schedule
15-30 mg PO q8-12h
0.1-0.2 mg/kg max 15 mg IV q4h
0.5-2 mg or 0.01-0.02 mg/kg initial bolus IV/IM/SL/SC or via ETT (2-2.5x IV dose), increase dose by 2 mg until response/max 10 mg
acute angina: 0.3-0.6 mg SL q5min, OR 5 μg/min IV increasing
by 5-20 μg/min q3-5min
1-2 tabs PO q6h prn
Status epilepticus: see Table 17
Apply to affected area bid-tid 0.25-1 mg/kg IV
2 puffs inhaled q4-6h max 12 puffs/d
100 mg IV/IM initially, then 50-100 mg IM/IV/PO OD x 3d
1-2 tabs PO q4-6h prn
Indications
Mild to moderate acute/chronic pain Prescribed in combination with NSAIDs or acetaminophen
Comatose patient
Opioid overdose
Reversal in procedural sedation
Angina Acute MI
Moderate pain control Status epilepticus
Superficial infections
Procedural sedation, also refractory status epilepticus
Asthma Reactive airways
To treat/prevent Wernicke’s encephalopathy Pain control
Comments
GI and constipation side effects DO NOT CRUSH, CUT, or CHEW Risk of tolerance
If patient is a chronic opioid user begin with very small doses, and go up with small increments as needed
Not to be used with other antihypertensives Not in right ventricular MI
Oxycodone + acetaminophen Max 4 g acetaminophen daily
Begin maintenance dose 12 h after loading dose Continuous ECG, BP monitoring mandatory
Short acting
Anesthetic/sedative (complication=apnea, decreased BP)
Caution with cardiac abnormalities Caution use in pregnancy
Acetaminophen + Codeine
Metabolism of codeine is highly variable Max 4 g acetaminophen daily
  






















































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